Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801059 | 0.75 | ALDH1A1 (0.48) | KMT2AGAAMEN1SMN1; SMN2HPGD | |
| SCHEMBL10850245 | 0.72 | MAPT (0.47) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL17975326 | 0.72 | GAA (0.52) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL5923306 | 0.71 | ALDH1A1 (0.48) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL6925014 | 0.71 | TAAR1 (0.44) | MAPTKMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL2829448 | 0.71 | KMT2A (0.43) | MAPTKMT2ACYP1A2CASP1 | |
| SCHEMBL10853491 | 0.69 | MAPT (0.44) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL5923376 | 0.68 | EPHX2 (0.49) | MAPTKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL6182511 | 0.68 | KMT2A (0.47) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL3455095 | 0.68 | MAPT (0.55) | MAPTKMT2AGAAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |