Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801059 | 0.81 | ALDH1A1 (0.48) | TAAR1SMN1; SMN2RAB9ALMNAHIF1A | |
| SCHEMBL6829066 | 0.79 | IKBKB (0.35) | SMN1; SMN2RAB9ALMNATSHRMAPT | |
| SCHEMBL13498020 | 0.77 | RAB9A (0.62) | SMN1; SMN2RAB9ALMNATSHRMAPT | |
| SCHEMBL5923511 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ALMNATSHRMAPT | |
| SCHEMBL5923376 | 0.74 | EPHX2 (0.49) | LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL6925018 | 0.73 | MEN1 (0.50) | TAAR1P2RX7SMN1; SMN2RAB9ALMNA | |
| SCHEMBL5923306 | 0.72 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ALMNATSHRMAPT | |
| SCHEMBL5923052 | 0.71 | VCP (0.46) | SMN1; SMN2RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL14868788 | 0.71 | TAAR1 (0.49) | TAAR1P2RX7SMN1; SMN2RAB9ACNR1 | |
| SCHEMBL6183354 | 0.71 | MAPT (0.41) | SMN1; SMN2RAB9ALMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037166-A2 | THERAPEUTIC GUANIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |