Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6082145 | 0.85 | L3MBTL1 (0.38) | NCF1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6081552 | 0.83 | NCF1 (0.43) | NCF1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4243183 | 0.81 | PIK3R2 (0.37) | NCF1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6083397 | 0.73 | GAA (0.40) | KDM4EALDH1A1 | |
| SCHEMBL6082378 | 0.73 | GAA (0.36) | KDM4EALDH1A1 | |
| SCHEMBL6082840 | 0.71 | NR4A2 (0.41) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8337393 | 0.71 | NCF1 (0.45) | NCF1MEN1KMT2AMAPTL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6082140 | 0.71 | L3MBTL1 (0.39) | NCF1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6082440 | 0.71 | CD38 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6224003 | 0.68 | PIK3R2 (0.39) | NCF1MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523480-A2 | DERIVATIVES OF 3-GUANIDINOCARBONYL-1-HETEROARYL-PYRROLE, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | Aventis Pharma Deutschland GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004007478-A2 | DERIVATIVES OF 3-GUANIDINOCARBONYL-1-HETEROARYL-PYRROLE, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-22 | — | — | WO | disclosed |