Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 5/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339628 | 0.80 | SLC9A1 (0.46) | NCF1ADRB2SLC9A1 | |
| SCHEMBL6081552 | 0.80 | NCF1 (0.43) | NCF1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL8348273 | 0.76 | NCF1 (0.44) | NCF1HTR5AMEN1KMT2AADRB2 | |
| SCHEMBL14098939 | 0.71 | NCF1 (0.59) | NCF1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL6183790 | 0.71 | NCF1 (0.37) | NCF1MEN1KMT2APIK3R2MAPT | |
| SCHEMBL8340484 | 0.71 | COMT (0.55) | NCF1SLC9A1MAPT | |
| SCHEMBL8336852 | 0.70 | MEN1 (0.46) | NCF1MEN1KMT2AADRB2MAPT | |
| SCHEMBL8338997 | 0.67 | HTR5A (0.41) | HTR5ASLC9A1MAPK1L3MBTL1 | |
| SCHEMBL8339462 | 0.67 | HTR5A (0.44) | HTR5ASLC9A1 | |
| SCHEMBL6082840 | 0.67 | NR4A2 (0.41) | MEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007478-A2 | DERIVATIVES OF 3-GUANIDINOCARBONYL-1-HETEROARYL-PYRROLE, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-22 | — | — | WO | disclosed |