Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 17/20 | 0.56 |
| ▸ | HTR7 | P34969 | 17/20 | 0.56 |
| ▸ | HTR6 | P50406 | 17/20 | 0.56 |
| ▸ | DRD2 | P14416 | 16/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7226979 | 0.99 | HTR2A (0.55) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL6182991 | 0.97 | HTR2A (0.53) | HTR2AHTR7HTR6DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL7225841 | 0.96 | HTR2A (0.52) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL6184263 | 0.84 | ABCB1 (0.51) | HTR2AHTR7HTR6HTR1A | |
| SCHEMBL6184834 | 0.84 | DRD2 (0.51) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL6183970 | 0.82 | TBXA2R (0.56) | — | |
| SCHEMBL6182420 | 0.81 | ABCB1 (0.50) | HTR7 | |
| SCHEMBL7225838 | 0.81 | DRD2 (0.57) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL6185306 | 0.80 | HTR1A (0.48) | HTR2AHTR7HTR6DRD2HTR1A | |
| SCHEMBL6183084 | 0.80 | TBXA2R (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |