SCHEMBL6184366

SCHEMBL6184366

COc1ccccc1C1(CN)CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 11/20 0.59
SLC6A4 P31645 9/20 0.59
SLC6A2 P23975 6/20 0.59
DPP4 P27487 1/20 0.49
SIGMAR1 Q99720 1/20 0.44
HTT P42858 1/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6185182 0.98 SLC6A3 (0.58) SLC6A3SLC6A4SLC6A2DPP4SIGMAR1
SCHEMBL2332969 0.95 SLC6A3 (0.53) SLC6A3SLC6A4SLC6A2DPP4SIGMAR1
SCHEMBL34463017 0.91 SLC6A4 (0.47) SLC6A3SLC6A4SLC6A2DPP4SIGMAR1
SCHEMBL2339483 0.91 SLC6A4 (0.47) SLC6A3SLC6A4SLC6A2DPP4SIGMAR1
SCHEMBL11310169 0.83 SIGMAR1 (0.44) SLC6A3SLC6A4SLC6A2SIGMAR1HTT
SCHEMBL9355631 0.82 SIGMAR1 (0.43) SLC6A3SLC6A4SLC6A2SIGMAR1HTT
SCHEMBL10612019 0.78 CNR1 (0.43) SLC6A3SLC6A4SLC6A2SIGMAR1HTT
SCHEMBL11919524 0.75 SIGMAR1 (0.49) SIGMAR1HTTALDH1A1KMT2A
SCHEMBL6803384 0.75 SLC6A3 (0.62) SLC6A3SLC6A4SLC6A2DPP4
SCHEMBL3405893 0.75 SLC6A3 (0.62) SLC6A3SLC6A4SLC6A2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501800-A1 BOMBESIN ANTAGONISTS Warner-Lambert Company LLC (US) 2005-02-02 EP disclosed
US-20040063643-A1 Bombesin antagonists PFIZER INC. 2004-04-01 US disclosed
WO-2003092670-A1 BOMBESIN ANTAGONISTS WARNER-LAMBERT COMPANY LLC (US) 2003-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063643-A1 Bombesin antagonists BRS3, NPSR1, GNRHR SLC6A3 465/4885SLC6A4 419/4885SLC6A2 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.