Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201319 | 0.77 | KDM4E (0.41) | KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4442743 | 0.73 | KDM4E (0.35) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2203576 | 0.71 | MEN1 (0.56) | MEN1KMT2A | |
| SCHEMBL6188024 | 0.71 | REN (0.31) | SSTR4 | |
| SCHEMBL1255261 | 0.69 | KDM4E (0.40) | KDM4E | |
| SCHEMBL571789 | 0.69 | SLC18A3 (0.41) | KDM4EMAPT | |
| SCHEMBL1254418 | 0.68 | KDM1A (0.45) | KDM4EMAPT | |
| SCHEMBL1254662 | 0.67 | TAAR1 (0.41) | KDM4E | |
| SCHEMBL4777417 | 0.67 | BCHE (0.33) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2583636 | 0.67 | CYP3A4 (0.42) | KDM4EMAPTMEN1KMT2ASSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558608-A1 | OXINDOLE SUBSTITUTED PIPERAZINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037820-A1 | OXINDOLE SUBSTITUTED PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-05-06 | — | — | WO | disclosed |