Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357942 | 0.73 | HTR2A (0.44) | KCNH2 | |
| SCHEMBL31357998 | 0.73 | HTR2A (0.44) | KCNH2 | |
| SCHEMBL6801582 | 0.73 | SSTR4 (0.35) | SSTR4 | |
| SCHEMBL6816969 | 0.73 | HTR2A (0.44) | KCNH2 | |
| SCHEMBL14685960 | 0.72 | MEN1 (0.43) | KCNH2 | |
| Hydrochloric Acid SCHEMBL8463063 | 0.71 | HTR2C (0.43) | KCNH2 | |
| SCHEMBL6184493 | 0.71 | KDM4E (0.33) | SSTR4 | |
| SCHEMBL571789 | 0.69 | SLC18A3 (0.41) | — | |
| SCHEMBL1254418 | 0.68 | KDM1A (0.45) | — | |
| SCHEMBL2202696 | 0.68 | MPO (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558608-A1 | OXINDOLE SUBSTITUTED PIPERAZINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037820-A1 | OXINDOLE SUBSTITUTED PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-05-06 | — | — | WO | disclosed |