Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | C5 | P01031 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184777 | 1.00 | TOP1 (0.34) | TOP1KCNH2KDM4EHPGDJAK2 | |
| SCHEMBL6183281 | 0.90 | LMNA (0.36) | TOP1KDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL6183285 | 0.90 | LMNA (0.36) | TOP1KDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL6181606 | 0.78 | KCNH2 (0.33) | TOP1KCNH2KDM4EHPGDLMNA | |
| SCHEMBL6181610 | 0.78 | KCNH2 (0.33) | TOP1KCNH2KDM4EHPGDLMNA | |
| SCHEMBL6183620 | 0.68 | DRD2 (0.35) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6183624 | 0.68 | DRD2 (0.35) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6184374 | 0.66 | KDM4E (0.33) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| Biphenyl SCHEMBL2838222 | 0.61 | AKR1C2 (0.47) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL25465736 | 0.61 | KDM4E (0.47) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143407-A1 | Process for porducing quinolonecarboxylic acid derivative | DAIICHI PHARMACEUTICAL CO., LTD (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1518856-A1 | PROCESS FOR PRODUCING QUINOLONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143407-A1 | Process for porducing quinolonecarboxylic acid derivative | PORCN, POR, COASY | TOP1 47/4885KCNH2 2106/4885KDM4E 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.