Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185078 | 0.93 | PPARG (0.53) | FFAR1FFAR4HPGDNPSR1PPARG | |
| SCHEMBL6182314 | 0.90 | TSHR (0.45) | FFAR1FFAR4HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6184768 | 0.85 | TSHR (0.44) | FFAR4HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6186189 | 0.83 | HRH1 (0.45) | HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6185286 | 0.79 | HRH1 (0.46) | — | |
| SCHEMBL6187569 | 0.78 | HRH1 (0.53) | HPGDRAB9A | |
| SCHEMBL6187276 | 0.78 | HRH1 (0.45) | — | |
| SCHEMBL6185364 | 0.78 | KDM4E (0.46) | — | |
| SCHEMBL6185131 | 0.75 | CASP3 (0.52) | RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16689220 | 0.74 | LMNA (0.69) | FFAR1FFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |