Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 17/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185000 | 0.83 | F10 (0.41) | CTSLCTSBCTSS | |
| SCHEMBL6185005 | 0.83 | F10 (0.41) | CTSLCTSBCTSS | |
| SCHEMBL6406102 | 0.80 | MEN1 (0.39) | CTSLCTSBCTSS | |
| SCHEMBL5523334 | 0.79 | CTSS (0.46) | CTSLCTSS | |
| SCHEMBL6189089 | 0.79 | F10 (0.40) | CTSLCTSBCTSS | |
| SCHEMBL6190599 | 0.74 | CTSS (0.47) | CTSLCTSBCTSS | |
| SCHEMBL6190597 | 0.74 | CTSS (0.47) | CTSLCTSBCTSS | |
| SCHEMBL6186263 | 0.74 | CTSK (0.40) | CTSLCTSBCTSS | |
| SCHEMBL6186265 | 0.74 | CTSK (0.40) | CTSLCTSBCTSS | |
| SCHEMBL5523879 | 0.72 | CTSS (0.66) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539725-A1 | 3-(3,5-DISUBSTITUTED-4-HYDROXYPHENYL)PROPIONAMIDE DERIVATIVES AS CATHEPSIN B INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004026851-A1 | 3-(3,5-DISUBSTITUTED-4-HYDROXYPHENYL)PROPIONAMIDE DERIVATIVES AS CATHEPSIN B INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-04-01 | — | — | WO | disclosed |