Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.65 |
| ▸ | HTR2C | P28335 | 12/20 | 0.65 |
| ▸ | HTR2B | P41595 | 12/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21850578 | 0.91 | HTR2A (0.54) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL24620372 | 0.91 | HTR2A (0.54) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL29557860 | 0.88 | HTR2C (0.51) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL3162737 | 0.87 | HTR2A (0.74) | HTR2AHTR2CHTR2BADCY6ADCY3 | |
| Hydrochloric Acid SCHEMBL4247274 | 0.85 | HTR2A (0.71) | HTR2AHTR2CHTR2BADCY6ADCY3 | |
| SCHEMBL7527046 | 0.83 | ALDH1A1 (0.48) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL20231622 | 0.83 | L3MBTL1 (0.48) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL21468497 | 0.82 | ALDH1A1 (0.47) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL6122379 | 0.82 | POLB (0.47) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL719964 | 0.80 | ADCY6 (0.56) | HTR2AHTR2CHTR2BL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549639-A1 | SULPHONAMIDE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004031181-A1 | SULFONAMIDE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2004-04-15 | — | — | WO | disclosed |