Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206844 | 0.86 | PRKCI (0.40) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL3355963 | 0.84 | PRKCI (0.39) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL3352601 | 0.84 | PRKCI (0.39) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL5349926 | 0.83 | PRKCI (0.38) | PRKCICA12PPARA | |
| Acetic Acid SCHEMBL6139766 | 0.82 | PRKCI (0.41) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| Formamide SCHEMBL6342969 | 0.81 | PRKCI (0.36) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6647805 | 0.77 | PRKCI (0.34) | ALDH1A1L3MBTL1MEN1KMT2AHSD17B10 | |
| SCHEMBL7123990 | 0.76 | PRKCI (0.40) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL8922421 | 0.74 | PRKCI (0.53) | ALDH1A1LMNAATMMEN1KMT2A | |
| SCHEMBL3909320 | 0.74 | CTSD (0.41) | ALDH1A1LMNAATML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050619-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2004-06-17 | — | — | WO | disclosed |