SCHEMBL3909320

SCHEMBL3909320

CCCc1c(CC)ccc(C(=O)OC)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.41
CYSLTR2 Q9NS75 7/20 0.41
CYSLTR1 Q9Y271 7/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
PDK2 Q15119 1/20 0.41
PDK4 Q16654 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
MITF O75030 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7041532 0.85 CA12 (0.46) CTSDCA12CA1CA2CA7
SCHEMBL8321013 0.84 CTSD (0.41) CTSDCA12CA1CA2CA7
SCHEMBL9728468 0.83 PPARG (0.48) CTSDCYSLTR2CYSLTR1PPARGPPARD
SCHEMBL9062684 0.81 CA12 (0.47) CA12CA1CA2CA7PDK2
SCHEMBL4016040 0.77 PPARG (0.41) CA12CA1CA2CA7PDK2
SCHEMBL8922421 0.77 PRKCI (0.53) CA12CA1CA2CA7PDK2
SCHEMBL19126030 0.77 PRKCI (0.42) CYSLTR2CYSLTR1CA12CA1CA2
SCHEMBL28879796 0.76 CA12 (0.42) CA12CA1CA2CA7PDK2
SCHEMBL8578774 0.76 ALDH1A1 (0.39) CA12CA1CA2CA7PDK2
SCHEMBL6274458 0.75 ALDH1A1 (0.51) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10300041-B2 Liquid oral simvastatin compositions ROSEMONT PHARMACEUTICALS LTD (GB) 2019-05-28 US disclosed
US-20170143669-A1 LIQUID ORAL COMPOSITIONS ROSEMONT PHARMACEUTICALS LTD. (GB) 2017-05-25 US disclosed
US-9597289-B2 Liquid oral simvastatin compositions ROSEMONT PHARMACEUTICALS LTD. (GB) 2017-03-21 US disclosed
US-20090311330-A1 LIQUID ORAL COMPOSITIONS ROSEMONT PHARMACEUTICALS LTD. (GB) 2009-12-17 US disclosed
EP-2018153-A1 LIQUID ORAL COMPOSITIONS Rosemont Pharmaceuticals Ltd (GB) 2009-01-28 EP disclosed
WO-2007125339-A1 LIQUID ORAL COMPOSITIONS ROSEMONT PHARMACEUTICALS LTD (GB) 2007-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090311330-A1 LIQUID ORAL COMPOSITIONS HMGCR, LIPA, PCSK9 CTSD 2652/4885CYSLTR2 1611/4885CYSLTR1 1697/4885
US-10300041-B2 Liquid oral simvastatin compositions APOB, HMGCR, PROC CTSD 2434/4885CYSLTR2 3500/4885CYSLTR1 2801/4885
US-20170143669-A1 LIQUID ORAL COMPOSITIONS HMGCR, APOB, PROC CTSD 2441/4885CYSLTR2 3301/4885CYSLTR1 2703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.