Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980101 | 0.78 | ALDH1A1 (0.37) | LMNAL3MBTL1TDP1MMP8ALDH1A1 | |
| SCHEMBL4809141 | 0.78 | ALDH1A1 (0.37) | LMNAL3MBTL1TDP1MMP8ALDH1A1 | |
| SCHEMBL4809892 | 0.78 | ALDH1A1 (0.37) | LMNAL3MBTL1TDP1MMP8ALDH1A1 | |
| SCHEMBL363983 | 0.72 | TSHR (0.48) | LMNATDP1MMP8CASP1NLRP3 | |
| SCHEMBL7509738 | 0.69 | MMP8 (0.51) | LMNATDP1MMP8CASP1NLRP3 | |
| SCHEMBL3822845 | 0.69 | TDP1 (0.42) | TDP1MMP8CASP1NLRP3PIN1 | |
| SCHEMBL16673419 | 0.68 | ESR1 (0.38) | LMNAL3MBTL1TDP1NLRP3KMT2A | |
| SCHEMBL1190661 | 0.68 | CASP1 (0.49) | LMNAL3MBTL1TDP1MMP8CASP1 | |
| SCHEMBL1127868 | 0.67 | MEN1 (0.59) | LMNACASP1PIN1KMT2AMEN1 | |
| SCHEMBL27755853 | 0.67 | TDP1 (0.45) | TDP1MMP8CASP1NLRP3PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | disclosed |