Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357942 | 1.00 | HTR2A (0.44) | HTR2AHTR2CKCNH2KDM1ACHRM1 | |
| SCHEMBL31357998 | 1.00 | HTR2A (0.44) | HTR2AHTR2CKCNH2KDM1ACHRM1 | |
| SCHEMBL14685960 | 0.81 | MEN1 (0.43) | HTR2AHTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL8463063 | 0.80 | HTR2C (0.43) | HTR2AHTR2CKCNH2 | |
| SCHEMBL795369 | 0.73 | HTR2A (0.44) | HTR2AHTR2CKCNH2DRD2DRD3 | |
| SCHEMBL6188024 | 0.73 | REN (0.31) | KCNH2 | |
| SCHEMBL10902484 | 0.72 | HTR2A (0.45) | HTR2AHTR2CKCNH2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8679453 | 0.70 | MPO (0.52) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL27666015 | 0.69 | HTR2A (0.42) | HTR2AHTR2CKCNH2CHRM1HRH1 | |
| SCHEMBL381572 | 0.68 | SLC18A3 (0.59) | HTR2AHTR2CKCNH2KDM1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |
| WO-2004009591-A1 | A PROCESS FOR THE PREPARATION OF ANTIPSYCHOTIC RISPERIDONE | AUROBINDO PHARMA LTD. (IN) | 2004-01-29 | — | — | WO | disclosed |