Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186523 | 0.86 | BRD4 (0.45) | BRD4SLC6A4SLC6A3 | |
| SCHEMBL6077411 | 0.79 | LMNA (0.53) | BRD4CNR1MEN1KMT2ACYP2C19 | |
| SCHEMBL6186896 | 0.77 | PDPK1 (0.47) | BRD4CNR1SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL6186361 | 0.77 | PPARG (0.43) | BRD4SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL28419252 | 0.75 | BRD4 (0.55) | BRD4CNR1SLC6A4SLC6A3IDO1 | |
| SCHEMBL6187038 | 0.75 | BRD4 (0.50) | BRD4CNR1SLC6A4SLC6A3MEN1 | |
| SCHEMBL6192279 | 0.73 | BRD4 (0.45) | BRD4SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL6187841 | 0.72 | CYP2D6 (0.43) | SLC6A4SLC6A3IDO1TDO2MEN1 | |
| SCHEMBL3691019 | 0.71 | BRD4 (0.59) | BRD4CNR1SLC6A4SLC6A3IDO1 | |
| SCHEMBL10334603 | 0.70 | PDPK1 (0.60) | SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539685-A1 | MCP-1 RECEPTOR ANTAGONISTS AND METHOD OF USE THEREOF | Warner-Lambert Company LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004014847-A1 | MCP-1 RECEPTOR ANTAGONISTS AND METHOD OF USE THEREOF | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |