Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188068 | 0.77 | BRD4 (0.46) | SLC6A4SLC6A3CACNA2D1CACNB1CACNA1A | |
| SCHEMBL20544320 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1MAPTHSD17B10LMNA | |
| SCHEMBL23531383 | 0.73 | PDPK1 (0.44) | PDPK1SLC6A3POLBKDM4EALDH1A1 | |
| SCHEMBL11356933 | 0.72 | KMT2A (0.48) | PDPK1SLC6A4SLC6A3CNR1POLB | |
| SCHEMBL8895206 | 0.71 | PDPK1 (0.43) | PDPK1SLC6A3POLBKDM4EALDH1A1 | |
| SCHEMBL6186361 | 0.71 | PPARG (0.43) | SLC6A4SLC6A3BRD4 | |
| SCHEMBL20544211 | 0.70 | PDPK1 (0.60) | PDPK1SLC6A3FFAR1KDM4EALDH1A1 | |
| Chlorobenzene SCHEMBL27979453 | 0.70 | SCN4A (0.46) | KDM4EALDH1A1MAPTGABBR2GABBR1 | |
| SCHEMBL10334603 | 0.70 | PDPK1 (0.60) | PDPK1SLC6A4SLC6A3POLB | |
| SCHEMBL11733684 | 0.70 | NTSR1 (0.56) | PDPK1POLBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539685-A1 | MCP-1 RECEPTOR ANTAGONISTS AND METHOD OF USE THEREOF | Warner-Lambert Company LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004014847-A1 | MCP-1 RECEPTOR ANTAGONISTS AND METHOD OF USE THEREOF | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |