Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.70 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188080 | 0.83 | HTR6 (1.00) | HTR6HTR7HTR4HTR1ADRD2 | |
| SCHEMBL6185518 | 0.83 | HTR6 (1.00) | HTR6HTR7HTR4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6188510 | 0.82 | HTR6 (0.98) | HTR6HTR7HTR4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6189532 | 0.82 | HTR6 (0.98) | HTR6HTR7HTR4HTR1ADRD2 | |
| SCHEMBL6188091 | 0.80 | HTR6 (0.53) | HTR6 | |
| SCHEMBL6191274 | 0.79 | HTR6 (0.60) | HTR6 | |
| SCHEMBL6186114 | 0.77 | HTR6 (0.75) | HTR6HTR7HTR4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6186554 | 0.76 | HTR6 (0.74) | HTR6HTR7HTR4HTR1ADRD2 | |
| SCHEMBL6187575 | 0.75 | KMT2A (0.67) | HTR6 | |
| SCHEMBL31588161 | 0.75 | HTR6 (0.71) | HTR6HTR7HTR4HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994862-B1 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | claimed |