Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6191274 | 0.89 | HTR6 (0.60) | HTR6KMT2A | |
| SCHEMBL6187575 | 0.85 | KMT2A (0.67) | HTR6TSHRKMT2ACRHBPCRHR2 | |
| SCHEMBL6187429 | 0.82 | HTR6 (0.65) | HTR6POLBHTTKMT2A | |
| SCHEMBL6188084 | 0.80 | HTR6 (0.70) | HTR6 | |
| SCHEMBL6186532 | 0.79 | HTR6 (0.64) | HTR6KMT2A | |
| SCHEMBL6186261 | 0.77 | HTR6 (0.81) | HTR6KMT2A | |
| Hydrochloric Acid SCHEMBL6188261 | 0.77 | HTR6 (0.79) | HTR6KMT2A | |
| SCHEMBL6187548 | 0.77 | HTR6 (0.61) | HTR6KMT2A | |
| SCHEMBL6184853 | 0.75 | HTR6 (0.61) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6187851 | 0.74 | HTR6 (0.56) | HTR6POLBTSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994862-B1 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | claimed |