Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.83 |
| ▸ | NSD2 | O96028 | 6/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | CDC25A | P30304 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | MITF | O75030 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906861 | 0.82 | MAPT (0.75) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL22413322 | 0.82 | CDC25A (0.66) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL31277646 | 0.79 | MAPT (0.72) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL17249976 | 0.79 | CDC25A (1.00) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL17249965 | 0.78 | MAPT (1.00) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL31029510 | 0.78 | MAPT (0.66) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL10894074 | 0.78 | MAPT (0.66) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL7962344 | 0.78 | MAPT (0.70) | MAPTNPSR1MAPK1NSD2TDP1 | |
| SCHEMBL6190075 | 0.78 | MAPT (0.54) | MAPTNPSR1MAPK1HSP90AA1L3MBTL1 | |
| SCHEMBL12283411 | 0.76 | CDC25A (0.71) | MAPTNPSR1MAPK1NSD2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-04-12 | — | — | US | disclosed |
| EP-1256576-B1 | FUSED IMIDAZOLIUM DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6734203-B2 | ANTI-CANCERS AND ANTITUMOR AGENTS | ASTELLAS PHARMA INC. (JP) | 2004-05-11 | — | — | US | disclosed |
| US-20030114508-A1 | Fused imidazolium derivatives | ASTELLAS PHARMA INC. (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1256576-A1 | FUSED IMIDAZOLIUM DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | NES, CBR3, SQOR | MAPT 4120/4885NPSR1 1209/4885MAPK1 2109/4885 |
| US-20030114508-A1 | Fused imidazolium derivatives | TP53, HRAS, BCOR | MAPT 4795/4885NPSR1 4494/4885MAPK1 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.