Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190477 | 1.00 | DRD2 (0.37) | DRD2KCNH2NPC1RAB9ASLC6A4 | |
| SCHEMBL6189187 | 0.85 | CNR2 (0.41) | DRD2NPC1RAB9ACNR2NPY5R | |
| SCHEMBL6189190 | 0.85 | CNR2 (0.41) | DRD2NPC1RAB9ACNR2NPY5R | |
| SCHEMBL6186882 | 0.83 | CNR2 (0.35) | DRD2KCNH2NPC1RAB9ASLC6A4 | |
| SCHEMBL6186886 | 0.83 | CNR2 (0.35) | DRD2KCNH2NPC1RAB9ASLC6A4 | |
| SCHEMBL6188419 | 0.81 | DRD2 (0.39) | DRD2KCNH2NPC1RAB9ASLC6A4 | |
| SCHEMBL6190194 | 0.81 | DRD2 (0.44) | DRD2KCNH2NPC1RAB9ASLC6A4 | |
| SCHEMBL6190739 | 0.81 | P2RX3 (0.38) | CNR2NPY5RTHRBFEN1LMNA | |
| Hydrochloric Acid SCHEMBL6191041 | 0.74 | GMNN (0.52) | KCNH2LMNA | |
| Hydrochloric Acid SCHEMBL6191039 | 0.74 | GMNN (0.52) | KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |