Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186300 | 0.85 | SLC6A4 (0.38) | SLC6A4FEN1CNR2KDM1A | |
| SCHEMBL6189841 | 0.85 | PARP10 (0.36) | NPC1RAB9AFEN1CNR2KDM1A | |
| SCHEMBL6190194 | 0.85 | DRD2 (0.44) | DRD2NPC1RAB9ASLC6A4KCNH2 | |
| SCHEMBL6187144 | 0.81 | ALDH1A1 (0.51) | PARP15TNKS2PARP2 | |
| SCHEMBL6189036 | 0.81 | DRD2 (0.37) | DRD2NPC1RAB9ASLC6A4KCNH2 | |
| SCHEMBL6190227 | 0.81 | CNR2 (0.37) | SLC6A4KCNH2CNR2KDM1A | |
| SCHEMBL6190477 | 0.81 | DRD2 (0.37) | DRD2NPC1RAB9ASLC6A4KCNH2 | |
| SCHEMBL6187294 | 0.81 | F12 (0.41) | SLC6A4FEN1 | |
| SCHEMBL6190514 | 0.80 | MAPT (0.39) | NPY5R | |
| SCHEMBL6188183 | 0.79 | SCN4A (0.42) | KCNH2PIM1CNR2KDM1APIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |