SCHEMBL618904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL617788	0.89	KIT (0.47)	PTGS2ERN1ALDH1A1LMNAALOX15
	SCHEMBL619368	0.87	PTGS2 (0.41)	PTGS2ERN1ALDH1A1TUBB4ATUBB
	SCHEMBL10188877	0.87	PTGS2 (0.41)	PTGS2ERN1ALDH1A1LMNAALOX15
	SCHEMBL616273	0.78	PTGS2 (0.72)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL616949	0.78	PTGS2 (0.48)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL618775	0.78	TUBB4A (0.64)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL618535	0.78	TUBB4A (0.58)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL618366	0.78	PTGS2 (0.48)	PTGS2ALDH1A1NPC1TUBB4ATUBB
	SCHEMBL616176	0.77	PTGS2 (0.54)	PTGS2ALDH1A1MAPTTUBB4ATUBB
	SCHEMBL616937	0.77	PTGS2 (0.70)	PTGS2TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.