Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093451 | 0.89 | ACMSD (0.42) | ACMSDKMT2AADORA3ADORA2ACES2 | |
| SCHEMBL1515817 | 0.82 | CES2 (0.50) | ACMSDKMT2ACES2CES1SMN1; SMN2 | |
| SCHEMBL5211314 | 0.82 | CES2 (0.44) | ACMSDKMT2AADORA3ADORA2ACES2 | |
| SCHEMBL4074665 | 0.81 | ACMSD (0.54) | ACMSDNPSR1ALOX5APFEN1ALDH1A1 | |
| SCHEMBL12388490 | 0.78 | KDM4C (0.48) | ACMSDKMT2ANPC1RAB9APTPRC | |
| SCHEMBL11725835 | 0.74 | S100A4 (0.56) | KMT2AADORA3ADORA2ANPSR1SMN1; SMN2 | |
| SCHEMBL11308153 | 0.74 | S100A4 (0.56) | KMT2AADORA3ADORA2ACES2CES1 | |
| SCHEMBL13461 | 0.73 | CES2 (0.65) | KMT2ACES2CES1SMN1; SMN2GAA | |
| SCHEMBL29593208 | 0.73 | CES2 (0.65) | KMT2ACES2CES1SMN1; SMN2GAA | |
| SCHEMBL1515697 | 0.71 | ALOX5AP (0.59) | ACMSDALOX5APFEN1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567502-A1 | SUBSTITUTED DIHYDROPHENANTHRIDINESUL FONAMIDES | Wyeth (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050631-A1 | SUBSTITUTED DIHYDROPHENANTHRIDINESUL FONAMIDES | WYETH (US) | 2004-06-17 | — | — | WO | disclosed |