Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192699 | 0.89 | KDM4E (0.47) | CA2LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6191669 | 0.89 | GAA (0.50) | LMNANAMPTSMN1; SMN2PPARGPPARA | |
| SCHEMBL6189844 | 0.83 | RECQL (0.48) | LMNAKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL6190237 | 0.80 | GAA (0.43) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6677541 | 0.79 | CA2 (0.49) | CA1CA2LMNANAMPTKDM4E | |
| SCHEMBL6188262 | 0.79 | CA2 (0.44) | CA1CA2LMNANAMPTKDM4E | |
| SCHEMBL8199082 | 0.77 | NQO2 (0.44) | LMNATSHRIDO1MEN1KMT2A | |
| SCHEMBL14431419 | 0.77 | CA2 (0.52) | CA1CA2LMNANAMPTIDO1 | |
| SCHEMBL3658450 | 0.77 | ALDH1A1 (0.55) | LMNAKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL30313133 | 0.77 | ALDH1A1 (0.55) | LMNAKDM4EALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-B1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-6352982-B1 | TREATING DIABETES, OBESITY, OR INVETERATE DIARRHEA IN A MAMMAL WHICH COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-05 | — | — | US | disclosed |