Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198955 | 0.94 | BRD4 (0.40) | NQO2IDO1 | |
| SCHEMBL8206463 | 0.89 | KCNA5 (0.43) | — | |
| SCHEMBL8211311 | 0.84 | LMNA (0.45) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL8198952 | 0.79 | SYK (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL8197856 | 0.79 | MAPT (0.45) | LMNA | |
| SCHEMBL8197947 | 0.78 | IDO1 (0.41) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL6189525 | 0.77 | CA1 (0.45) | IDO1LMNAMEN1TSHRKMT2A | |
| SCHEMBL6189844 | 0.77 | RECQL (0.48) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL27536806 | 0.77 | SLC7A5 (0.41) | — | |
| SCHEMBL27536876 | 0.77 | GABRP (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252795-A | 4, 1-benzoxazepine *, their analogs and their use as somatostatin agonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-05-10 | — | — | CN | disclosed |
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |