Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.64 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192471 | 0.93 | GPR119 (0.55) | GPR119CHEK2USP30 | |
| SCHEMBL6192490 | 0.86 | GPR119 (0.62) | GPR119CHEK2 | |
| SCHEMBL19624304 | 0.85 | GPR119 (0.64) | GPR119CHEK2 | |
| SCHEMBL8546356 | 0.85 | GPR119 (0.60) | GPR119CHEK2USP30ALDH1A1 | |
| SCHEMBL76105 | 0.85 | YAP1 (0.60) | GPR119USP30 | |
| SCHEMBL5268593 | 0.84 | GPR119 (0.65) | GPR119CHEK2USP30ALDH1A1 | |
| SCHEMBL23465733 | 0.84 | GPR119 (0.62) | GPR119CHEK2ALDH1A1 | |
| SCHEMBL21023135 | 0.84 | GPR119 (0.62) | GPR119CHEK2 | |
| SCHEMBL75960 | 0.84 | GPR119 (0.62) | GPR119CHEK2USP30 | |
| SCHEMBL1649132 | 0.84 | GPR119 (0.64) | GPR119CHEK2USP30ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070714-A9 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20040006099-A1 | Amidine compounds | JAPAN TOBACCO INC. | 2004-01-08 | — | — | US | disclosed |
| US-6562828-B1 | Novel amidine compound having a blood coagulation factor Xa inhibitory activity | JAPAN TOBACCO INC. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1070714-A1 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006099-A1 | Amidine compounds | F2, SERPINC1, F12 | GPR119 2900/4885CHEK2 3493/4885USP30 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.