Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | TDO2 | P48775 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207670 | 0.92 | TSHR (0.48) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL1764658 | 0.83 | ESR1 (0.32) | LMNATDP1SLC6A3CYP2D6CYP2C9 | |
| SCHEMBL1500533 | 0.81 | TSHR (0.50) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL29200286 | 0.77 | TSHR (0.46) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL29013799 | 0.77 | TSHR (0.46) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL1411248 | 0.77 | TSHR (0.46) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL624797 | 0.77 | ADRB2 (0.56) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL11216352 | 0.75 | TYR (0.46) | HIF1ALMNAMAPK1TP53HPGD | |
| SCHEMBL2091212 | 0.75 | MAPK1 (0.50) | TSHRHIF1ALMNAMAPK1TDP1 | |
| SCHEMBL10989849 | 0.75 | ADRB2 (0.54) | TSHRHIF1ALMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651111-B | Preparation method of p-chlorobenzaldehyde | 新昌县泰如科技有限公司 | 2021-11-12 | — | — | CN | disclosed |
| US-10899687-B2 | Process for the preparation of organic halides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2021-01-26 | — | — | US | disclosed |
| EP-3359513-B1 | PROCESS FOR THE PREPARATION OF ORGANIC HALIDES | TECHNION RES & DEV FOUNDATION (IL) | 2020-12-30 | — | — | EP | disclosed |
| US-20180282247-A1 | PROCESS FOR THE PREPARATION OF ORGANIC HALIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-10-04 | — | — | US | disclosed |
| WO-2017060906-A1 | PROCESS FOR THE PREPARATION OF ORGANIC HALIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-04-13 | — | — | WO | disclosed |
| EP-0994862-B1 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | disclosed |
| US-6316450-B1 | PIPERAZINE COMPOUNDS FOR TREATING DEPRESSION AND ANXIETY | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-13 | — | — | US | disclosed |
| EP-0994862-A2 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999002502-A2 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 1999-01-21 | — | — | WO | disclosed |
| US-4731372-A | Aryl(aryloxy or arylthio) azolomethanes, and their use as pesticides | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| US-4720502-A | Aryl(aryloxy or arylthio)azolomethanes and their use as pesticides | THE DOW CHEMICAL COMPANY (US) | 1988-01-19 | — | — | US | disclosed |
| US-4717733-A | FUNGICIDES; PLANT GROWTH REGULATORS | THE DOW CHEMICAL COMPANY (US) | 1988-01-05 | — | — | US | disclosed |
| US-4717732-A | FUNGICIDES, PLANT GROWTH REGULATORS | THE DOW CHEMICAL COMPANY (US) | 1988-01-05 | — | — | US | disclosed |
| US-4717734-A | FUNGICIDES, PLANT GROWTH REGULATORS | THE DOW CHEMICAL COMPANY (US) | 1988-01-05 | — | — | US | disclosed |
| US-4716174-A | FUNGICIDES, INSECTICIDES, PLANT GROWTH REGULATORS | THE DOW CHEMICAL COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| US-4701207-A | PESTICIDES, PLANT GROWTH REGULATORS | THE DOW CHEMICAL COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4701463-A | FUNGICIDE, INSECTICIDE, PLANT GROWTH REGULATOR | THE DOW CHEMICAL COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4636514-A | PLANT GROWTH REGULATORS, PESTICIDES, FUNGICIDES, INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| EP-0101288-A2 | Aryl(aryloxy or arylthio)azolomethanes, their preparation and their use | THE DOW CHEMICAL COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10899687-B2 | Process for the preparation of organic halides | HDHD5, CBR3, RCC2 | TSHR 1084/4885HIF1A 2112/4885LMNA 3948/4885 |
| US-20180282247-A1 | PROCESS FOR THE PREPARATION OF ORGANIC HALIDES | HDHD5, CBR3, RCC2 | TSHR 1084/4885HIF1A 2112/4885LMNA 3948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.