Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190849 | 0.92 | TSHR (0.50) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL5395302 | 0.86 | CHRNB2 (0.35) | MAPK1TDP1TP53CYP19A1 | |
| SCHEMBL11209447 | 0.83 | RXRA (0.45) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL8545218 | 0.80 | ADRB2 (0.50) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL3952742 | 0.76 | CYP1A2 (0.73) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL11165087 | 0.76 | CYP1A2 (0.73) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL28215 | 0.76 | CYP1A2 (0.73) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL1764658 | 0.76 | ESR1 (0.32) | TDP1LMNACYP1A2 | |
| SCHEMBL12591826 | 0.76 | ADRB2 (0.56) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL679628 | 0.76 | ALDH1A1 (0.50) | MAPK1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041672-B1 | PROCESS FOR THE PREPARATION OF AROMATIC ALDEHYDES | BAYER AG (DE) | 1983-09-28 | — | — | EP | disclosed |
| EP-0041672-A1 | Process for the preparation of aromatic aldehydes | BAYER AG (DE) | 1981-12-16 | — | — | EP | disclosed |