Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901443 | 0.72 | POLB (0.46) | — | |
| SCHEMBL5993548 | 0.71 | — | — | |
| SCHEMBL3634855 | 0.63 | HTR6 (0.48) | — | |
| SCHEMBL6193617 | 0.63 | HTR6 (0.48) | — | |
| SCHEMBL6028975 | 0.63 | CYP3A4 (0.41) | — | |
| SCHEMBL6192035 | 0.62 | SLC6A2 (0.45) | — | |
| SCHEMBL6260656 | 0.62 | SLC6A2 (0.45) | — | |
| SCHEMBL6195075 | 0.62 | SLC6A2 (0.41) | HRH4 | |
| SCHEMBL6191516 | 0.61 | SCN9A (0.35) | — | |
| SCHEMBL16826808 | 0.59 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583751-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES | CV THERAPEUTICS, INC. (US) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004069818-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES | CV THERAPEUTICS INC. (US) | 2004-08-19 | — | — | WO | disclosed |