Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194746 | 0.88 | MAOB (0.42) | MAOBEDNRASMN1; SMN2MAPK1HSD17B2 | |
| SCHEMBL6193627 | 0.83 | HTT (0.49) | SMN1; SMN2MEN1KMT2AHPGDHTT | |
| SCHEMBL6194103 | 0.80 | MAOB (0.48) | MAOBEDNRASMN1; SMN2KMT2AHPGD | |
| SCHEMBL6198797 | 0.79 | MAOB (0.37) | MAOBEDNRASMN1; SMN2MAPK1HSD17B2 | |
| SCHEMBL6194984 | 0.78 | MAPK1 (0.45) | SMN1; SMN2MAPK1HSD17B2USP2ALPG | |
| SCHEMBL6196253 | 0.76 | MAPT (0.43) | SMN1; SMN2MEN1KMT2AHPGDHTT | |
| SCHEMBL6196408 | 0.74 | ALDH1A1 (0.44) | MAOBSMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL2118544 | 0.72 | SMN1; SMN2 (0.47) | MAOBSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL6197234 | 0.72 | EDNRA (0.36) | MAOBEDNRASMN1; SMN2MAPK1HSD17B2 | |
| SCHEMBL6196949 | 0.70 | HTT (0.43) | MAOBSMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0768302-A2 | Hydroxypyridinones | Novartis AG (CH) | 1997-04-16 | — | — | EP | disclosed |