Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193627 | 0.89 | HTT (0.49) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6198669 | 0.87 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6193308 | 0.85 | HTT (0.39) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6196408 | 0.81 | ALDH1A1 (0.44) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL30669323 | 0.77 | MEN1 (0.57) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL30669400 | 0.77 | MEN1 (0.57) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6200128 | 0.77 | LMNA (0.50) | SMN1; SMN2HTTKMT2AMEN1HPGD | |
| SCHEMBL6200148 | 0.77 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6197503 | 0.77 | ALDH1A1 (0.34) | SMN1; SMN2HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6193376 | 0.76 | MAOB (0.45) | MAPTSMN1; SMN2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0768302-A2 | Hydroxypyridinones | Novartis AG (CH) | 1997-04-16 | — | — | EP | disclosed |