Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458350 | 1.00 | PDIA6 (0.59) | PDIA6FFAR4PTGES2CA1CA2 | |
| SCHEMBL29839101 | 0.87 | PDIA6 (0.45) | PDIA6FFAR4PTGES2CA1CA2 | |
| SCHEMBL30540027 | 0.83 | FFAR4 (0.46) | PDIA6FFAR4WDR5EPHX2HRH4 | |
| SCHEMBL3610385 | 0.83 | FFAR4 (0.46) | PDIA6FFAR4WDR5EPHX2HRH4 | |
| SCHEMBL1804729 | 0.79 | PDIA6 (0.67) | PDIA6FFAR4CA1CA2PTGS2 | |
| SCHEMBL29575651 | 0.79 | PDIA6 (0.67) | PDIA6FFAR4CA1CA2PTGS2 | |
| SCHEMBL14322000 | 0.78 | PDIA6 (0.54) | PDIA6PTGES2CA1CA2SMN1; SMN2 | |
| SCHEMBL27170907 | 0.78 | PDIA6 (0.54) | PDIA6PTGES2CA1CA2PTGS2 | |
| SCHEMBL20773327 | 0.78 | PTGES2 (0.47) | FFAR4PTGES2CA1CA2SLC6A4 | |
| SCHEMBL29651895 | 0.78 | PTGES2 (0.47) | PTGES2CA1CA2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521746-A1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X-Ceptor Therapeutics, Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003076418-A1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-09-18 | — | — | WO | disclosed |