Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196375 | 0.87 | PDIA6 (0.59) | PDIA6FFAR4WDR5EPHX2HRH4 | |
| SCHEMBL29458350 | 0.87 | PDIA6 (0.59) | PDIA6FFAR4WDR5EPHX2HRH4 | |
| SCHEMBL30540027 | 0.81 | FFAR4 (0.46) | PDIA6FFAR4BCHEACHEWDR5 | |
| SCHEMBL3610385 | 0.81 | FFAR4 (0.46) | PDIA6FFAR4BCHEACHEWDR5 | |
| SCHEMBL22056762 | 0.74 | DDR1 (0.40) | PDIA6FFAR4BCHEACHEEPHX2 | |
| SCHEMBL31514006 | 0.74 | DDR1 (0.40) | PDIA6FFAR4BCHEACHEEPHX2 | |
| SCHEMBL13439935 | 0.73 | GPR3 (0.44) | FFAR4HRH4GPR3KIF11CES1 | |
| SCHEMBL30867033 | 0.72 | GPR3 (0.49) | FFAR4HRH4GPR3KIF11CES1 | |
| SCHEMBL171112 | 0.72 | GPR3 (0.49) | FFAR4HRH4GPR3KIF11CES1 | |
| SCHEMBL15212079 | 0.71 | FFAR4 (0.46) | FFAR4BCHEACHEWDR5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288412-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | Rappta Therapeutics Oy (FI) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167866-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2022-08-11 | — | — | WO | disclosed |