Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27366785 | 0.70 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL31332052 | 0.70 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL4043872 | 0.70 | MTNR1A (0.47) | MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL3573632 | 0.70 | MTNR1A (0.52) | MTNR1AMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL20561917 | 0.69 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL14400281 | 0.68 | MTNR1A (0.61) | MTNR1AMTNR1BHTR2C | |
| Trifluoroacetic Acid SCHEMBL3571194 | 0.68 | MTNR1A (0.50) | MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL31331960 | 0.68 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL27366783 | 0.68 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL28892601 | 0.67 | MTNR1A (0.56) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |