Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574051 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3571186 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL29845458 | 0.75 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL3572912 | 0.71 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL5264658 | 0.70 | KCNH2 (0.47) | MTNR1AMTNR1B | |
| SCHEMBL6196659 | 0.70 | MTNR1A (0.49) | MTNR1AMTNR1BHTR2C | |
| Trifluoroacetic Acid SCHEMBL3571194 | 0.69 | MTNR1A (0.50) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7311973 | 0.67 | BTK (0.42) | — | |
| SCHEMBL4491260 | 0.67 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL3577828 | 0.67 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | disclosed |
| US-20060189604-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189604-A1 | Compounds | ELANE, PIGS, SDHA | MTNR1A 4164/4885MTNR1B 4015/4885HTR2C 1963/4885 |
| US-20100081650-A1 | Antimicrobial Compounds | ELANE, NISCH, PIGS | MTNR1A 4104/4885MTNR1B 4079/4885HTR2C 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.