SCHEMBL6196855

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6198437	0.92	ITGAL (0.50)	ITGALITGB2ICAM1ADRA1DSLC6A3
	SCHEMBL5830027	0.89	ITGAL (0.48)	ITGALITGB2ICAM1ADRA1DSLC6A3
	SCHEMBL6196799	0.89	LMNA (0.39)	ITGALITGB2ICAM1LMNAMAPT
	SCHEMBL6198480	0.86	ITGB2 (0.64)	ITGALITGB2ICAM1
	SCHEMBL6197134	0.84	ITGB2 (0.43)	ITGALITGB2ICAM1ADRA1DSLC6A3
	SCHEMBL27557315	0.84	SLC9A1 (0.44)	ITGALITGB2ICAM1ADRA1DSLC6A3
	SCHEMBL6196465	0.84	ITGAL (0.53)	ITGALITGB2ICAM1LMNAMAPT
	SCHEMBL5836083	0.82	ITGAL (0.41)	ITGALITGB2ICAM1LMNAHPGD
	SCHEMBL6199338	0.82	ITGAL (0.43)	ITGALITGB2ICAM1ADRA1DSLC6A3
	SCHEMBL6200004	0.81	ITGB2 (0.50)	ITGALITGB2ICAM1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.