Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551097 | 0.89 | HPRT1 (0.61) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL30184794 | 0.79 | ALDH1A1 (0.50) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL6831899 | 0.79 | ALDH1A1 (0.50) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL4582431 | 0.75 | ALDH1A1 (0.48) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL619740 | 0.75 | ALDH1A1 (0.46) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL2686125 | 0.75 | CYP1A2 (0.48) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL8967366 | 0.75 | ALDH1A1 (0.46) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL8967728 | 0.75 | ALDH1A1 (0.46) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL8637485 | 0.74 | CA12 (0.35) | ALDH1A1HSD17B10CYP2A6TDP1HPGD | |
| SCHEMBL711370 | 0.71 | ALDH1A1 (0.42) | CYP1A2HPRT1ALDH1A1HSD17B10CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396122-A2 | Ambient temperature curable polyorganosiloxanes | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1990-11-07 | — | — | EP | claimed |
| JP-2308857-A | — | — | None | — | — | JP | disclosed |
| CN-107082761-B | Phenanthridinone or benzophenanthridinone derivative and synthesis method thereof | 上海大学 | 2020-04-03 | — | — | CN | disclosed |
| EP-2344552-B1 | METHOD FOR PREPARING ELASTOMERIC COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2018-08-01 | — | — | EP | disclosed |
| EP-2324067-B1 | ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2018-04-25 | — | — | EP | disclosed |
| CN-107216349-A | A kind of preparation method of five-membered cyclic disiloxane compound | 杭州师范大学 | 2017-09-29 | — | — | CN | disclosed |
| US-8791221-B2 | Addition-curable metallosiloxane compound | DAICEL CORPORATION (JP) | 2014-07-29 | — | — | US | disclosed |
| EP-2650319-A1 | ADDITION-CURABLE METALLOSILOXANE COMPOUND | Daicel Corporation (JP) | 2013-10-16 | — | — | EP | disclosed |
| US-20130267653-A1 | ADDITION-CURABLE METALLOSILOXANE COMPOUND | DAICEL CORPORATION (JP) | 2013-10-10 | — | — | US | disclosed |
| US-8436113-B2 | Ethylene alpha olefin polymer formed by use of metallocene catalyst | SK INNOVATIONS CO., LTD. (KR) | 2013-05-07 | — | — | US | disclosed |
| WO-2010053264-A2 | METHOD FOR PREPARING ELASTOMERIC COPOLYMERS OF ETHYLENE AND α-OLEFINS | SK ENERGY CO., LTD. (KR) | 2010-05-14 | — | — | WO | disclosed |
| US-20100120981-A1 | ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2010-05-13 | — | — | US | disclosed |
| US-20100113720-A1 | METHOD FOR PREPARING ELASTOMERIC COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2010-05-06 | — | — | US | disclosed |
| WO-2010030145-A2 | ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME | SK ENERGY CO., LTD. (KR) | 2010-03-18 | — | — | WO | disclosed |
| US-7670733-B2 | Silanol containing photoconductors | XEROX CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080268356-A1 | Silanol containing photoconductors | XEROX CORPORATION. | 2008-10-30 | — | — | US | disclosed |
| US-20080107983-A1 | Overcoated photoconductors with thiophosphate containing photogenerating layer | XEROX CORPORATION | 2008-05-08 | — | — | US | disclosed |
| US-20080107985-A1 | Silanol containing overcoated photoconductors | XEROX CORPORATION | 2008-05-08 | — | — | US | disclosed |
| CN-101105646-A | Silanol containing photoconductors | XEROX CORP (US) | 2008-01-16 | — | — | CN | disclosed |
| JP-H02308857-A | ROOM-TEMPERATURE-CURING POLYORGANOSILOXANE | UNION CARBIDE CHEM & PLAST CO INC | 1990-12-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267653-A1 | ADDITION-CURABLE METALLOSILOXANE COMPOUND | B2M, MSI2, MNS1 | CYP1A2 3597/4885HPRT1 3249/4885ALDH1A1 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.