SCHEMBL8637485

SCHEMBL8637485

O[SiH2]c1ccccc1[SiH2]O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CA14 Q9ULX7 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
GMNN O75496 1/20 0.35
ALDH1A1 P00352 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.35
MMP9 P14780 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8018541 0.81
SCHEMBL6114402 0.78
SCHEMBL8707470 0.78
SCHEMBL23045193 0.78
Iodide SCHEMBL8899157 0.76 CES2 (0.37) TDP1SMN1; SMN2NPC1ALDH1A1ALOX15
SCHEMBL18921876 0.74 ALDH1A1 (0.48) MAPTHPGDSMN1; SMN2HSD17B10ALDH1A1
Phenol SCHEMBL9576252 0.73 CA12 (0.52) CA12CA2CA3CA4TDP1
SCHEMBL15655352 0.73 ALDH1A1 (0.50) CA2TDP1MAPTSMN1; SMN2HSD17B10
SCHEMBL11017963 0.73 HSPA5 (0.32)
SCHEMBL15533828 0.73 GABRA1 (0.50) CA12CA2HPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10182835-A None JP disclosed
US-10995268-B2 Etching composition effective to selectively wet etch a silicon nitride film LTCAM CO., LTD. (KR) 2021-05-04 US disclosed
JP-H10182835-A PHENYLSILYL-CROSS-LINKED POLYSILAZANE AND ITS PRODUCTION TONEN CORP 1998-07-07 JP disclosed