Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197829 | 1.00 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6177706 | 0.77 | RAB9A (0.45) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5732897 | 0.75 | POLB (0.46) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5736112 | 0.69 | HSP90AA1 (0.36) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5736262 | 0.68 | HSP90AA1 (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6180221 | 0.67 | RAB9A (0.47) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL602247 | 0.66 | ALDH1A1 (0.61) | KMT2ANPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL602246 | 0.66 | ALDH1A1 (0.61) | KMT2ANPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5734192 | 0.66 | CYP19A1 (0.45) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL9073991 | 0.66 | ALDH1A1 (0.52) | KMT2ANPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320522-B1 | COMPOSITIONS AND METHODS OF THE USE THEREOF ACHIRAL ANALOGUES OF CC-1065 AND THE DUOCARMYCINS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |