Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199950 | 0.84 | KDM4E (0.41) | KDM4EASPHKDM8GABRPGABRD | |
| Hydrochloric Acid SCHEMBL6083555 | 0.83 | KDM4E (0.40) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL6201155 | 0.82 | THRB (0.45) | KDM4EALDH1A1GAA | |
| SCHEMBL27471079 | 0.82 | TET2 (0.40) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL3869645 | 0.81 | LMNA (0.42) | KDM4EASPHKDM8DHODHALDH1A1 | |
| SCHEMBL21836559 | 0.79 | ALOX5AP (0.39) | KDM4EASPHKDM8DHODHALDH1A1 | |
| SCHEMBL6201203 | 0.78 | KDM4E (0.41) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL24619660 | 0.77 | KDM4E (0.46) | KDM4EASPHKDM8CSNK2A1DHODH | |
| SCHEMBL6198659 | 0.75 | ALB (0.51) | KDM4EASPHKDM8CSNK2A1LDHA | |
| SCHEMBL6198572 | 0.74 | PTGS2 (0.44) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | disclosed |
| CN-1128790-C | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents | UPJOHN CO (US) | 2003-11-26 | — | — | CN | disclosed |
| CN-1281439-A | 4-hydroxyquinoline-3-carboxamide and hydrazide compounds as antiviral agents | UPJOHN CO (US) | 2001-01-24 | — | — | CN | disclosed |
| EP-1042295-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| US-6093732-A | PREVENT HERPESVIRAL INFECTIONS, PARTICULARLY, HUMAN CYTOMEGALOVIRAL INFECTION | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1999032450-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |