Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200061 | 0.89 | KMO (0.43) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6197595 | 0.81 | ITGAL (0.46) | POLBITGB2ICAM1ITGAL | |
| SCHEMBL6201623 | 0.80 | RAB9A (0.47) | ALDH1A1KDM4ESMN1; SMN2MEN1POLB | |
| SCHEMBL6195509 | 0.79 | CCNC (0.36) | ALDH1A1HTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL6311336 | 0.79 | POLB (0.44) | POLBITGB2ICAM1ITGAL | |
| SCHEMBL6318617 | 0.75 | RAB9A (0.49) | ALDH1A1KDM4ESMN1; SMN2POLBITGB2 | |
| SCHEMBL6318242 | 0.75 | POLB (0.42) | POLBITGB2ICAM1ITGALAKR1C3 | |
| SCHEMBL6317608 | 0.74 | RAB9A (0.48) | KDM4EPOLBITGB2ICAM1ITGAL | |
| SCHEMBL6317511 | 0.74 | LGMN (0.43) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL6917194 | 0.73 | RAB9A (0.52) | SMN1; SMN2MEN1POLBKMT2AITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | disclosed |