Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848492 | 0.89 | AURKA (0.44) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6846664 | 0.87 | AURKA (0.55) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6200264 | 0.86 | AURKA (0.64) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203305 | 0.82 | AURKA (0.49) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6199702 | 0.80 | AURKA (0.78) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6204384 | 0.79 | AURKA (0.44) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6848519 | 0.78 | CKS1B (0.43) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6198489 | 0.78 | ALDH1A1 (0.47) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203462 | 0.76 | AURKA (0.42) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6201006 | 0.76 | AURKA (0.66) | AURKAALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425283-B1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-03-16 | — | — | EP | disclosed |