Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198397 | 0.87 | AURKA (0.50) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6200961 | 0.86 | AURKA (0.71) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203305 | 0.86 | AURKA (0.49) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6201890 | 0.82 | AURKA (0.51) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6202459 | 0.80 | ALDH1A1 (0.53) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6202985 | 0.79 | AURKA (0.87) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6204384 | 0.76 | AURKA (0.44) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6848492 | 0.76 | AURKA (0.44) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6202056 | 0.75 | AURKA (0.51) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203462 | 0.74 | AURKA (0.42) | AURKAALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | DPYD, TPMT, TYMP | AURKA 795/4885ALDH1A1 176/4885HPGD 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.