Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848519 | 0.86 | CKS1B (0.43) | AURKAEGFRLRRK2STK4STK3 | |
| Hydrochloric Acid SCHEMBL6204384 | 0.86 | AURKA (0.44) | AURKAEGFRLRRK2STK4STK3 | |
| SCHEMBL6201890 | 0.83 | AURKA (0.51) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6201006 | 0.77 | AURKA (0.66) | AURKAEGFRLRRK2STK4STK3 | |
| SCHEMBL6198397 | 0.76 | AURKA (0.50) | AURKALRRK2STK4STK3ALDH1A1 | |
| SCHEMBL6848492 | 0.76 | AURKA (0.44) | AURKALRRK2STK4STK3ALDH1A1 | |
| SCHEMBL6202620 | 0.74 | AURKA (0.60) | AURKAEGFRLRRK2STK4STK3 | |
| SCHEMBL6846664 | 0.74 | AURKA (0.55) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6200951 | 0.73 | AURKA (0.59) | AURKAEGFRLRRK2STK4STK3 | |
| SCHEMBL6201973 | 0.73 | AURKA (0.56) | AURKAEGFRALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425283-B1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-03-16 | — | — | EP | disclosed |