Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196499 | 0.96 | CCR5 (0.39) | TACR2KMT2ALMNACNR1CCR5 | |
| SCHEMBL6202591 | 0.96 | TACR2 (0.38) | TACR2KMT2ALMNACCR5SLC6A2 | |
| SCHEMBL6201334 | 0.95 | CCR5 (0.39) | TACR2KMT2ALMNACNR1CCR5 | |
| SCHEMBL6197643 | 0.90 | RECQL (0.43) | CCR5GAASMN1; SMN2 | |
| SCHEMBL8113330 | 0.87 | TACR2 (0.35) | TACR2KMT2ASLC6A2SLC6A4MEN1 | |
| SCHEMBL6197826 | 0.87 | KMT2A (0.38) | TACR2KMT2ACNR1SLC6A2SLC6A4 | |
| SCHEMBL4630697 | 0.85 | TACR2 (0.50) | TACR2 | |
| SCHEMBL6199172 | 0.84 | SLC6A2 (0.42) | TACR2KMT2ACNR1SLC6A2SLC6A4 | |
| SCHEMBL6196495 | 0.83 | CYP3A4 (0.38) | KMT2ACCR5SLC6A2SLC6A4MEN1 | |
| SCHEMBL6202589 | 0.83 | KMT2A (0.37) | KMT2ASLC6A2SLC6A4MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048658-B1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | SANKYO CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6288059-B1 | ANTIASTHMATIC, ANTIALLERGEN AGENTS; URINARY INCONTINENCE; NATURAL KILLER CELL RECEPTOR AND TACHYKININ ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1048658-A1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | Sankyo Company Limited (JP) | 2000-11-02 | — | — | EP | disclosed |