Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 6/20 | 0.41 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199169 | 0.90 | TACR2 (0.39) | CCR5GAASMN1; SMN2 | |
| SCHEMBL6197638 | 0.90 | RECQL (0.43) | RECQLSTSCCR5HPGDGAA | |
| SCHEMBL6199632 | 0.89 | RECQL (0.47) | RECQLSTSCCR5HPGD | |
| SCHEMBL6202591 | 0.89 | TACR2 (0.38) | CCR5 | |
| SCHEMBL6196499 | 0.89 | CCR5 (0.39) | CCR5 | |
| SCHEMBL6201334 | 0.88 | CCR5 (0.39) | CCR5 | |
| SCHEMBL6196196 | 0.87 | ALDH1A1 (0.40) | CCR5 | |
| SCHEMBL8113330 | 0.80 | TACR2 (0.35) | — | |
| SCHEMBL6200549 | 0.79 | CCR5 (0.41) | CCR5 | |
| SCHEMBL7499000 | 0.79 | CCR5 (0.41) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048658-B1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | SANKYO CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6288059-B1 | ANTIASTHMATIC, ANTIALLERGEN AGENTS; URINARY INCONTINENCE; NATURAL KILLER CELL RECEPTOR AND TACHYKININ ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1048658-A1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | Sankyo Company Limited (JP) | 2000-11-02 | — | — | EP | disclosed |