Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15602827 | 0.83 | SGMS2 (0.52) | MAPK1MAOBALDH1A1XDHMAPT | |
| SCHEMBL6200588 | 0.81 | PTPN1 (0.64) | PTPN1MAPTL3MBTL1 | |
| SCHEMBL8896541 | 0.81 | PTPN1 (0.72) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL6198469 | 0.80 | PTPN1 (0.63) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL6200654 | 0.80 | PTPN1 (0.63) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL6199219 | 0.80 | PTPN1 (0.63) | PTPN1MAPK1MAOBBRD4ALDH1A1 | |
| SCHEMBL6199847 | 0.80 | PTPN1 (0.63) | PTPN1MAPK1MAOBBRD4ALDH1A1 | |
| Fluoride SCHEMBL28325117 | 0.78 | MAOB (0.56) | MAPK1MAOBXDHMAPTTDP1 | |
| SCHEMBL12988735 | 0.78 | MAOB (0.70) | PTPN1MAOBXDH | |
| SCHEMBL6200447 | 0.77 | PTPN1 (0.60) | PTPN1MAPK1MAOBBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |