SCHEMBL619937

SCHEMBL619937

Cc1cccc2[nH]c(=O)oc(=O)c12

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.52
CFD P00746 1/20 0.52
ELANE P08246 7/20 0.46
OGT O15294 1/20 0.46
PDGFRA P16234 1/20 0.42
MAPK8 P45983 1/20 0.42
CDK5 Q00535 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
DAO P14920 1/20 0.42
NOS1 P29475 3/20 0.41
NOS2 P35228 2/20 0.41
NOS3 P29474 1/20 0.41
ESR2 Q92731 1/20 0.40
CYP1A2 P05177 1/20 0.40
AR P10275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3498795 0.81 F2 (0.52) F2CFDELANEOGTPDGFRA
SCHEMBL4509421 0.79 F2 (0.49) F2CFDELANEOGTPDGFRA
SCHEMBL434293 0.79 OGT (0.50) F2CFDOGTPDGFRAMAPK8
SCHEMBL1203402 0.78 F2 (0.52) F2CFDELANEOGTPDGFRA
SCHEMBL17203101 0.78 F2 (0.52) F2CFDELANEOGTPDGFRA
SCHEMBL147448 0.78 F2 (0.52) F2CFDELANEOGTDAO
SCHEMBL4492747 0.78 NOS1 (0.44) F2CFDOGTPDGFRAMAPK8
SCHEMBL3987671 0.78 F2 (0.52) F2CFDOGTPDGFRAMAPK8
SCHEMBL5310423 0.78 F2 (0.52) F2CFDOGTPDGFRAMAPK8
SCHEMBL1559364 0.77 ABCG2 (0.54) F2CFDELANEOGTAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120079371-A Oxygen vacancy-containing tungsten trioxide catalyst and preparation method and application thereof 南京理工大学 2025-06-03 CN claimed
CN-119098205-A Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof 南京理工大学 2024-12-10 CN claimed
CN-118910629-A Electrochemical synthesis method of quinazolinone derivative 齐齐哈尔医学院 2024-11-08 CN claimed
CN-118727475-A Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2024-10-01 CN claimed
CN-117625272-A Gear oil composition 中国石油化工股份有限公司 2024-03-01 CN claimed
CN-117625250-A Scale inhibition composition and application thereof 中国石油化工股份有限公司 2024-03-01 CN claimed
CN-117625288-A Lubricating oil composition special for unmanned aerial vehicle 中国石油化工股份有限公司 2024-03-01 CN claimed
CN-117603144-A Synthesis method of polysubstituted quinazolinone 常熟泓德生物科技有限公司 2024-02-27 CN claimed
CN-116063589-A Soot ashless dispersant, and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-110372611-B Method for selectively synthesizing polysubstituted dihydro quinazolinone or quinazolinone 常熟理工学院 2021-05-04 CN claimed
CN-110372611-A A kind of method of the polysubstituted dihydroquinazoline ketone of selectivity synthesis or quinazolinone 常熟理工学院 2019-10-25 CN claimed
CN-1257161-C Meptazinol prodrug and its salts and its production method UNIV FUDAN (CN) 2006-05-24 CN claimed
CN-1569839-A Meptazinol prodrug and its salts and its production method UNIV FUDAN (CN) 2005-01-26 CN claimed
EP-4727923-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIV GEORGIA (US) 2026-04-09 US disclosed
EP-4652154-A1 NOVEL ALPK1 INHIBITORS Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) 2025-11-26 EP disclosed
US-4346032-A ANTIDOTES TO OVERDOSES OF BENZODIAZEPINE TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1982-08-24 US disclosed
EP-0049711-A1 Process for the production of nitro-amino-benzenes BAYER AG (DE) 1982-04-21 EP disclosed
US-4316839-A Imidazodiazepine derivatives HOFFMAN-LA ROCHE INC. (US) 1982-02-23 US disclosed
EP-0027214-A1 Imidazodiazepine derivatives, process and intermediates for their preparation, medicaments containing them and their therapeutic application F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA CD47, SLC11A2, G6PD F2 1060/4885CFD 398/4885ELANE 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.